脳卒中に伴う後天的な失読症。アプリ+左下前頭回への陽極tDCSの効果。Randomized trial of iReadMore word reading training and brain stimulation in central alexia https://academic.oup.com/brain/advance-article/doi/10.1093/brain/awy138/5035882?rss=1…
posted at 22:12:13
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脳卒中に伴う後天的な失読症。アプリ+左下前頭回への陽極tDCSの効果。Randomized trial of iReadMore word reading training and brain stimulation in central alexia https://academic.oup.com/brain/advance-article/doi/10.1093/brain/awy138/5035882?rss=1…
posted at 22:12:13
セットの一部として恣意的に項目や課題をグループ化すると、(不)完全性に関する知覚が変わり、進展半ばの状態を完全には遠く感じやすくなり、疑似セットが終わるまで項目・課題に取り組む動機づけが高まる。Pseudo-set framing.
https://www.ncbi.nlm.nih.gov/pubmed/28967777
posted at 21:20:14
メタ分析を3つ実施。
・ビデオゲームのスキルと認知能力の相関関係
・ゲーマーと非ゲーマーの認知能力の差
・ビデオゲームの訓練が認知能力に与える影響
3つのいずれにおいても効果量は小さいか全くない。
Video game training does not enhance cognitive ability: https://www.ncbi.nlm.nih.gov/pubmed/29239631
posted at 20:59:28
C型肝炎ウイルス感染女性の子供は早産、低出生体重児であることが未感染女性よりも多い。Hepatitis C Virus Screening Among Children Exposed During Pregnancy
http://pediatrics.aappublications.org/content/141/6/e20173273…
posted at 20:49:36
An Exploratory Analysis of a Five Minute Speech Sample of Mothers of Children with Selective Mutism http://stars.library.ucf.edu/etd/5806/
posted at 18:27:39
金玉の温度って体温より~ 3 °C低いのか。知らなかった。The thermo-sensitive gene expression signatures of spermatogenesis https://rbej.biomedcentral.com/articles/10.1186/s12958-018-0372-8…
posted at 17:34:25
精子のDNA断片化が30%を超えると妊娠は望めない。Associations of sperm DNA fragmentation with lifestyle factors and semen parameters of Saudi men and its impact on ICSI outcome
https://rbej.biomedcentral.com/articles/10.1186/s12958-018-0369-3…
posted at 17:24:59
肥満関連のホルモン濃度と生殖機能障害との関係。レビュー。Role of hormonal and inflammatory alterations in obesity-related reproductive dysfunction at the level of the hypothalamic-pituitary-ovarian axis
https://rbej.biomedcentral.com/articles/10.1186/s12958-018-0366-6…
posted at 16:46:07
アンケート分析入門: Excelによる集計・評価・分析 https://amzn.to/2yhWMm5
posted at 14:13:31
「キャラ」概念の広がりと深まりに向けて https://amzn.to/2LZ11oe
posted at 14:13:04
Asperger's Children: The Origins of Autism in Nazi Vienna https://amzn.to/2LYkQfG
posted at 14:12:44
PACAP neurons in the ventral premammillary nucleus regulate reproductive function in the female mouse
https://elifesciences.org/articles/35960
posted at 13:45:38
外側上オリーブ核の主ニューロンは音が発生した時にしか活動しない。Principal cells of the brainstem's interaural sound level detector are temporal differentiators rather than integrators
https://elifesciences.org/articles/33854
posted at 13:36:34
The miR-590/Acvr2a/Terf1 Axis Regulates Telomere Elongation and Pluripotency of Mouse iPSCs
https://www.cell.com/stem-cell-reports/fulltext/S2213-6711(18)30225-X…
posted at 13:17:12
Human Clinical-Grade Parthenogenetic ESC-Derived Dopaminergic Neurons Recover Locomotive Defects of Nonhuman Primate Models of Parkinson's Disease
https://www.cell.com/stem-cell-reports/fulltext/S2213-6711(18)30227-3…
posted at 13:13:59
Persistent Sodium Current Mediates the Steep Voltage Dependence of Spatial Coding in Hippocampal Pyramidal Neurons
https://www.cell.com/neuron/fulltext/S0896-6273(18)30423-9…
posted at 13:05:32
Attractor Dynamics in Networks with Learning Rules Inferred from In Vivo Data
https://www.cell.com/neuron/fulltext/S0896-6273(18)30436-7…
posted at 12:57:50
ターゲット場所への探索に内側嗅内皮質第2層-歯状回の活動が必要。オプトジェネティクス。A Visual-Cue-Dependent Memory Circuit for Place Navigation
https://www.cell.com/neuron/fulltext/S0896-6273(18)30419-7…
posted at 12:49:27
Biallelic Mutations in MYORG Cause Autosomal Recessive Primary Familial Brain Calcification
https://www.cell.com/neuron/fulltext/S0896-6273(18)30435-5…
posted at 12:41:26
The Organization of Projections from Olfactory Glomeruli onto Higher-Order Neurons
https://www.cell.com/neuron/fulltext/S0896-6273(18)30383-0…
posted at 12:35:10
Feature-Based Visual Short-Term Memory Is Widely Distributed and Hierarchically Organized
https://www.cell.com/neuron/fulltext/S0896-6273(18)30424-0…
posted at 12:31:29
Competition for Space Is Controlled by Apoptosis-Induced Change of Local Epithelial Topology
https://www.cell.com/current-biology/fulltext/S0960-9822(18)30631-6…
posted at 12:11:22
Encoding of Target Detection during Visual Search by Single Neurons in the Human Brain
https://www.cell.com/current-biology/fulltext/S0960-9822(18)30564-5…
posted at 11:56:34
Reconfiguration of a Multi-oscillator Network by Light in the Drosophila Circadian Clock
https://www.cell.com/current-biology/fulltext/S0960-9822(18)30536-0…
posted at 11:52:48
Activity-Dependent Actin Remodeling at the Base of Dendritic Spines Promotes Microtubule Entry
https://www.cell.com/current-biology/fulltext/S0960-9822(18)30606-7…
posted at 11:49:40
Modulating Cell Fate as a Therapeutic Strategy
https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(18)30227-3…
posted at 11:45:30
Short-Term Fasting Reveals Amino Acid Metabolism as a Major Sex-Discriminating Factor in the Liver
https://www.cell.com/cell-metabolism/fulltext/S1550-4131(18)30328-0…
posted at 11:38:02
乳腺の脂肪細胞は妊娠中に前脂肪様細胞や線維芽様細胞になる。離乳で脂肪細胞に戻る。これは何回妊娠しても同じ。Reversible De-differentiation of Mature White Adipocytes into Preadipocyte-like Precursors during Lactation
https://www.cell.com/cell-metabolism/fulltext/S1550-4131(18)30329-2…
posted at 11:34:39
Supra-Additive Effects of Combining Fat and Carbohydrate on Food Reward
https://www.cell.com/cell-metabolism/fulltext/S1550-4131(18)30325-5…
posted at 11:28:06
Postprandial Oxidative Metabolism of Human Brown Fat Indicates Thermogenesis
https://www.cell.com/cell-metabolism/fulltext/S1550-4131(18)30327-9…
posted at 11:21:10
キイロショウジョウバエの脳において、高齢だとニューロンアイデンティティには影響しないが、RNA内容物が減る。 A Single-Cell Transcriptome Atlas of the Aging Drosophila Brain
https://www.cell.com/cell/fulltext/S0092-8674(18)30720-7…
posted at 11:15:38
A Milieu Molecule for TGF-β Required for Microglia Function in the Nervous System
https://www.cell.com/cell/fulltext/S0092-8674(18)30639-1…
posted at 11:12:07
統合失調症と双極性障害の両方に関与する遺伝子座はシナプスや神経経路に関わるもので114箇所 etc。Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes
https://www.cell.com/cell/fulltext/S0092-8674(18)30658-5…
posted at 11:03:25
軽度の浸透圧性下痢でも腸内細菌叢が変化。Transient Osmotic Perturbation Causes Long-Term Alteration to the Gut Microbiota
https://www.cell.com/cell/fulltext/S0092-8674(18)30585-3…
posted at 10:57:38
Common Disease Is More Complex Than Implied by the Core Gene Omnigenic Model
https://www.cell.com/cell/fulltext/S0092-8674(18)30714-1…
posted at 10:48:39
アイルランドにおいて、青銅時代でも人類の活動は環境に重大な影響をもたらした。Anthropogenic changes to the Holocene nitrogen cycle in Ireland
http://advances.sciencemag.org/content/4/6/eaas9383…
posted at 10:36:19
Reactivation of recall-induced neurons contributes to remote fear memory attenuation
http://science.sciencemag.org/content/360/6394/1239…
posted at 10:17:09
脳が大きい人は前頭頭頂の皮質ネットワークやそれと関連する皮質下領域が広い(vs. 辺縁系、感覚系、運動系)。これは子供の頃からあって、代謝コストや神経結合の高さと関連。Normative brain size variation and brain shape diversity in humans
http://science.sciencemag.org/content/360/6394/1222…
posted at 10:02:58
Synapse-specific representation of the identity of overlapping memory engrams
http://science.sciencemag.org/content/360/6394/1227…
posted at 09:55:01
野生の哺乳類、ヒトのせいで夜型傾向が強まる。メタ分析。この影響は、大陸、生息地、動物分類、ヒトの活動によって違うとはいえない。The influence of human disturbance on wildlife nocturnality
http://science.sciencemag.org/content/360/6394/1232…
posted at 09:50:20
遠赤光で光合成。Photochemistry beyond the red limit in chlorophyll f–containing photosystems
http://science.sciencemag.org/content/360/6394/1210…
posted at 09:32:39
Neural scene representation and rendering
http://science.sciencemag.org/content/360/6394/1204…
posted at 08:44:36
SOCE mediated by STIM and Orai is essential for pacemaker activity in the interstitial cells of Cajal in the gastrointestinal tract
http://stke.sciencemag.org/content/11/534/eaaq0918…
posted at 07:38:44
Multi-parametric quantitative MRI reveals three different white matter subtypes
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0196297…
posted at 07:17:56
Development of a Hybrid Course on Wheelchair Service Provision for clinicians in international contexts
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0199251…
posted at 06:17:38
Is the sky the limit? On the expansion threshold of a species’ range
http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.2005372…
posted at 06:10:58
Tellurium notebooks—An environment for reproducible dynamical modeling in systems biology
http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1006220…
posted at 05:47:38
身体感覚の信号検出課題でヒットに報酬を与え、ミスを罰することでフォールス・アラームが増加。正しく拒否したら報酬を与え、フォールス・アラームを罰することで、フォールス・アラームが低下。他の体性感覚課題に転移しない。聴覚課題への転移は弱いエビデンス。https://www.ncbi.nlm.nih.gov/pubmed/28967763?dopt=Abstract…
posted at 05:44:09
既婚の3歳児、妊娠している男性など、エラーなどであり得ない変数が出た時の扱い方。Bayesian Simultaneous Edit and Imputation for Multivariate Categorical Data
https://www.tandfonline.com/doi/abs/10.1080/01621459.2016.1231612?af=R&journalCode=uasa20…
posted at 04:48:43
A meta-analytic review of two modes of learning and the description-experience gap.
https://www.ncbi.nlm.nih.gov/pubmed/29239630
posted at 04:37:03
超早産児でも気管支肺異形成症にならなかった子と比較して気管支肺異形成症になった子は、認知、言語、実行機能が低く、学業不良で、ソーシャルスキルに難があり、健康関連QoLが低い。Cognitive Development and Quality of Life Associated With BPD in 10-Year-Olds Born…
http://pediatrics.aappublications.org/content/141/6/e20172719…
posted at 04:31:19
サバクトビバッタは群生すると、転写産物の発現が高い。RNA-Seq reveals large quantitative differences between the transcriptomes of outbreak and non-outbreak locusts
https://www.nature.com/articles/s41598-018-27565-0…
posted at 03:20:54
Musical Competence is Predicted by Music Training, Cognitive Abilities, and Personality
https://www.nature.com/articles/s41598-018-27571-2…
posted at 03:08:25
Ex vivo biomechanical characterization of syringe-needle ejections for intracerebral cell delivery
https://www.nature.com/articles/s41598-018-27568-x…
posted at 02:58:49
Structural Neural Correlates of Physiological Mirror Activity During Isometric Contractions of Non-Dominant Hand Muscles
https://www.nature.com/articles/s41598-018-27471-5…
posted at 02:54:15
Early-life and pubertal stress differentially modulate grey matter development in human adolescents
https://www.nature.com/articles/s41598-018-27439-5…
posted at 02:39:12
アフリカデバネズミでは社交性が高いよりも孤独の個体の方が脳が大きいし、前脳ニューロンも多い。Sociality does not drive the evolution of large brains in eusocial African mole-rats
https://www.nature.com/articles/s41598-018-26062-8…
posted at 02:34:18
Place Cell-Like Activity in the Primary Sensorimotor and Premotor Cortex During Monkey Whole-Body Navigation
https://www.nature.com/articles/s41598-018-27472-4…
posted at 02:26:22
Administration of molecular hydrogen during pregnancy improves behavioral abnormalities of offspring in a maternal immune activation model
https://www.nature.com/articles/s41598-018-27626-4…
posted at 02:19:16
Effects of 8-week sensory electrical stimulation combined with motor training on EEG-EMG coherence and motor function in individuals with stroke
https://www.nature.com/articles/s41598-018-27553-4…
posted at 02:12:02
Foveal Crowding Resolved
https://www.nature.com/articles/s41598-018-27480-4…
posted at 02:03:53
診療のタイミング歴などから次の診察でアルツハイマー病になっているかどうか99%超の正確性で予測。Predictive Modeling of the Progression of Alzheimer’s Disease with Recurrent Neural Networks
https://www.nature.com/articles/s41598-018-27337-w…
posted at 01:50:55
教育でバーチャルリアリティーを活用。Immersive VR and Education: Embodied Design Principles that Include Gesture and Hand Controls
https://www.frontiersin.org/articles/10.3389/frobt.2018.00081/abstract…
posted at 01:42:04
Risk factors for recent suicide attempts in major depressive disorder patients in China: results from a national study
https://www.frontiersin.org/articles/10.3389/fpsyt.2018.00300/abstract…
posted at 01:37:15
Cannabis, a significant risk factor for violent behavior in the early phase psychosis. Subheading : Two patterns of interaction of factors increase the risk of violent behavior: cannabis use disorder and impulsivity; cannabis use disorder, lack of…
https://www.frontiersin.org/articles/10.3389/fpsyt.2018.00294/abstract…
posted at 01:32:31
統合失調症患者で癌罹患率が低いのにmiR-137が関係するかもしれない。Association of MIR137 with symptom severity and cognitive functioning in belarusian schizophrenia patients.
https://www.frontiersin.org/articles/10.3389/fpsyt.2018.00295/abstract…
posted at 01:26:47
Regional cerebral blood flow in mania: assessment using 320-slice computed tomography
https://www.frontiersin.org/articles/10.3389/fpsyt.2018.00296/abstract…
posted at 01:21:50
A Randomised Trial of Personalised Cognitive-Behaviour Therapy for Alcohol Use Disorder in a Public Health Clinic
https://www.frontiersin.org/articles/10.3389/fpsyt.2018.00297/abstract…
posted at 01:18:54
Introjective individuals tend towards anhedonia: Self-report and experimental evidence
https://www.frontiersin.org/articles/10.3389/fpsyt.2018.00298/abstract…
posted at 01:13:26
癌誘発うつには炎症、HPA軸、グルタミン酸興奮毒性が関わる。レビュー。Biological Mechanisms of Cancer-Induced Depression
https://www.frontiersin.org/articles/10.3389/fpsyt.2018.00299/abstract…
posted at 01:08:11
Beyond rehabilitation of acuity, ocular alignment and binocularity in infantile strabismus
https://www.frontiersin.org/articles/10.3389/fnsys.2018.00029/abstract…
posted at 00:51:43
拒食症患者へのtDCS。New treatment perspectives in adolescents with Anorexia nervosa: the efficacy of non-invasive brain-directed treatment
https://www.frontiersin.org/articles/10.3389/fnbeh.2018.00133/abstract…
posted at 00:17:25
Chronic social stress leads to reduced gustatory reward salience and effort valuation in mice
https://www.frontiersin.org/articles/10.3389/fnbeh.2018.00134/abstract…
posted at 00:13:57
動物だと環境を豊かにすると、脳卒中からの機能的回復が促進されるという研究があるが、ヒトではどうか?レビュー。Is environmental enrichment ready for clinical application in human post-stroke rehabilitation?
https://www.frontiersin.org/articles/10.3389/fnbeh.2018.00135/abstract…
posted at 00:08:50
Maternal Predator Odor Exposure in Mice Programs Adult Offspring Social Behavior and Increases Stress-Induced Behaviors in Semi-Naturalistic and Commonly-Used Laboratory Tasks
https://www.frontiersin.org/articles/10.3389/fnbeh.2018.00136/abstract…
posted at 00:00:01